Aug 30, 2012

Needle Free Vaccination Via Nanoparticle Aerosols

 Prepare chemically and physically stable PNAPs economically and in a scalable fashion, using vaccine candidates that range from protein to attenuated whole bacteria. Investigators intend to show that their process of spray drying can produce dry vaccine powders with at least the cost efficiency of freeze drying, and can produce substantially purer active vaccine substance for delivery.
  Deliver via PNAP formulations large masses of antigen to the bronchopulmonary mucosa of infants and adults. Investigators intend to show that by formulating vaccines in PNAP aerosols, up to 100 mg of vaccine can be delivered to the pulmonary mucosa in several breaths, requiring less than a minute.